… two Sen1 mutants, while fast Pol II transcription exacerbates these phenotypes. Our findings
indicate that a balance between Pol II … the window for efficient termination. Perturbations of …

… Here we investigate the universality of the torpedo model of pol II termination in human cells
… tested two central predictions of the torpedo model for RNA pol II transcription termination (…

… for Sen1-dependent termination and poly(A)-dependent termination is broadly available
to target Pol II … is likely to be determined by kinetic competition between phosphorylation-specific …

… In addition, we show that Sen1-dependent termination strictly requires CTD recognition by …
action in the context of a kinetic competition between termination and elongation. We also find …

… to the RNA polymerase II (RNAPII) for efficient termination. We … Sen1-dependent transcription
termination and a rationale for the kinetic competition between elongation and termination…

… RNA polymerase II (Pol II) in budding yeast uses two major … conditions, rather than
competitive binding, we observed … (D) ChIP analysis showing Pol II kinetics of accumulation in …

… statistical and kinetic analysis of Pol II interactions with a … the kinetics of extrinsic eukaryotic
transcription termination … cerevisiae RNA Polymerase II (Pol II) was purified from a strain that …

… between NRD, histone -ubiquitylation, -methylation and -acetylation appear to provide a kinetic
control-step prior to Pol II … 1B) that involves competition between Ser5P and Ser2P acting …

… Pol II maintaining a pool of free enzyme able to compete for unoccupied promoters. Correct
termination also prevents Pol II … is depleted from the nucleus with similar kinetics (Figure 1C). …

… gene-body pausing by RNA polymerase II (Pol II), the key … between the splicing and
transcription machineries suggests that transcription elongation could impact splicing through kinetic …